New York, New York - July 11, 2012 - Investorideas.com, an investor
research portal specializing in sector research including biotech and
pharma stocks, issues a snapshot of recent news from biopharma stocks
reporting developments for the treatment of lung cancer. Sunshine
Biopharma Inc. (
OTCBB: SBFM) reported news on its lead compound, Adva-27a and OncoGenex Pharmaceuticals, Inc. (
NASDAQ: OGXI) announced an update on its lead product, custirsen.
According to OncoGenex's press release, "Lung cancer is the second
most common cancer in both men and women and the leading cause of
cancer-related death. Each year, more people die of lung cancer than of
colon, breast, and prostate cancers combined. This year, in the United
States alone, approximately 226,160 new cases of lung cancer will be
diagnosed and an estimated 160,340 patients will die of the disease. "
Sunshine Biopharma Inc. (
OTCBB: SBFM)
recently reported that it completed a cytotoxicity study of its lead
compound, Adva-27a, in H69AR, a Multidrug Resistant Small Cell Lung
Cancer cell line. Cytotoxicity studies measure the ability of a drug to
destroy cancer cells in vitro. The results of the study showed that
Adva-27a is significantly more effective at killing Multidrug Resistant
Small Cell Lung Cancer cells than Etoposide, the current commonly used
drug for this type of cancer.
Since reporting its news Sunshine Biopharma stock has more than doubled in recent trading and is currently trading at $0.54.
OncoGenex Pharmaceuticals, Inc. (
NASDAQ: OGXI)
reported news yesterday on the clinical development program for
custirsen and its plans to initiate a Phase 3 clinical trial in
non-small cell lung cancer (NSCLC).The trial, planned to begin
enrollment later this year, will evaluate the potential survival benefit
of combining custirsen with docetaxel, a standard second-line
chemotherapy treatment used in patients who have progressed after
initial, or first-line, treatment has failed.
The Phase 3 trial will be an international, randomized, open-label
study that will enroll approximately 1,100 patients with advanced or
metastatic NSCLC who have been previously treated with a first-line
platinum-based chemotherapy. Patients will be randomized to receive
custirsen plus docetaxel or docetaxel alone. The primary objective of
the study will be overall survival with additional secondary and
exploratory analyses of other efficacy outcomes and biomarker
relationships. Two formal interim analyses are planned for stopping the
trial early based on inadequate evidence of clinical benefit or
futility. No interim analyses for claiming efficacy are planned.
Custirsen, its lead product, is designed to block production of
clusterin, a cell survival protein that is commonly overexpressed in
several cancer types and in response to anticancer treatments.
OncoGenex Pharmaceuticals, Inc. (
NASDAQ: OGXI) is trading at $14.46, up 0.20 (1.40%) at the time of this report, with a morning high of $14.58.
About Sunshine Biopharma Inc. (OTCBB: SBFM):
Sunshine Biopharma is a pharmaceutical company focused on the
research, development and commercialization of drugs for the treatment
of various forms of cancer. The Company's lead compound, Adva-27a
targets aggressive forms of cancer.
www.sunshinebiopharma.com
About OncoGenex Pharmaceuticals (
NASDAQ: OGXI)
OncoGenex is a biopharmaceutical company committed to the
development and commercialization of new cancer therapies that address
treatment resistance in cancer patients. OncoGenex has a diverse
oncology pipeline, with each product candidate having a distinct
mechanism of action and representing a unique opportunity for cancer
drug development. OncoGenex and Teva Pharmaceutical Industries Ltd.
(NYSE: TEVA) have entered a global collaboration and license agreement
to develop and commercialize OncoGenex' lead drug candidate, custirsen.
Custirsen is currently in Phase 3 clinical development as a treatment in
men with metastatic castrate-resistant prostate cancer. OGX-427 is in
Phase 2 clinical development and OGX-225 is currently in pre-clinical
development.
www.OncoGenex.com.
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Learn more about Sunshine Biopharma Inc. (OTCBB:SBFM): Profile
Disclaimer/
Disclosure: The Investorideas.com is a third party publisher of news
and research Our sites do not make recommendations, but offer
information portals to research news, articles, stock lists and recent
research. Nothing on our sites should be construed as an offer or
solicitation to buy or sell products or securities. This site is
currently compensated by featured companies, news submissions and online
advertising. Disclosure: A third party on behalf of SBFM compensates
Investorideas.com for news release publishing and distribution : one
hundred thousand 144 shares for three months starting June 26th
BC Residents and Investor Disclaimer: Effective September 15 2008 -
all BC investors should review all OTC and Pink sheet listed companies
for adherence in new disclosure filings and filing appropriate documents
with Sedar. Read for more info:
http://www.bcsc.bc.ca/release.aspx?id=6894