Biotech Stock News; Aethlon Medical (OTCBB: AEMD) Note: A Medical Device Strategy to Address Metastatic Melanoma

SAN DIEGO - December 7, 2012 (Investorideas.com newswire) - Aethlon Medical, Inc. (OTCBB: AEMD), today released the following note authored by its Chairman and CEO, Jim Joyce.
At Aethlon Medical, our focus is to create revolutionary medical devices that save lives. In the treatment of Hepatitis C (HCV) infected individuals, we have demonstrated that our Hemopurifier® synergistically combines with drug therapy to accelerate the achievement of undetectable viral load. In cancer, I envision our opportunity to save lives will be driven by the discovery that our Hemopurifier® can addresses a therapeutic target that plays a pivotal role in cancer progression, yet remains beyond the reach of drug therapies. The target? Microvesicles known as exosomes, which are particles secreted by tumors underlying a wide-range of cancers.

When we first initiated our tumor-derived exosome research, it was based on a belief that these particles were immunosuppressive, much like glycoproteins that shed from HIV and other viral pathogens. However, the medical community consensus at the time was that exosomes had no biological function other than to discard cellular debris. Today, tumor-derived exosomes are known to suppress the immune response in cancer patients. Beyond possessing immunosuppressive properties, tumor-derived exosomes facilitate tumor growth, metastasis, and the development of drug resistance. Such deleterious effects underlie the pathogenesis of cancer, and as a result of our early research we have been able to obtain broad patent protection in the field. By addressing this unmet medical need, our objective is to deliver a medical device that improves the benefit of cancer therapies without adding drug resistance or interaction risks.
As more and more medical institutes establish exosome research programs, we benefit from new discoveries that will help us to understand which forms of cancer are most likely to benefit from our technology. In this regard, Dr. Annette Marleau (our Director of Tumor Immunology) provides the following review on recent discoveries that describe the implication of exosomes in metastatic melanoma, a form of cancer whose 5-year survival rate is less than 20%.
Exosomes As Therapeutic Targets In Metastatic Melanoma
Exosomes are nano-sized microvesicles released in large quantities by cancer cells that are key culprits in the pathogenesis of several cancer types. Exosomes are now recognized as biological delivery vehicles for communication between cells in almost every system of the body investigated to date. In the area of oncology, cancer derived exosomes are highly stable "packages" released from tumors that transport proteins and genetic material from their originating tumor cells to distant sites throughout the body to accelerate tumor progression. In melanoma patients, tumor-secreted exosomes serve as carriers of malignant proteins and their levels in circulation correlate with the aggressiveness of the cancer1. To date, cancer exosomes have been implicated in: a) immune suppression; b) enhancement of angiogenesis; and c) promotion of metastasis, which will be discussed below.
Owing to several recent publications that have defined their pathological roles in metastatic disease, melanoma exosomes are emerging as candidate therapeutic targets. Metastatic (stage 4) melanoma, the most aggressive form of skin cancer, has a five-year survival rate of only 15-20%2. This disease continues to be a challenge to treat, as the current standard treatments have proven to be ineffective and/or highly toxic. Since patients afflicted with metastatic melanoma have suppressed immune systems due to tumor- and drug-related effects, the efficacy of novel immunotherapeutic solutions is limited and only small percentages of patients experience durable responses and extended survival. Thus, the development of novel treatments to reliably bolster anti-cancer immune responses remains an urgent clinical objective.
Recent scientific studies have defined the importance of melanoma exosomes in the progression of cancer, thereby providing the rationale for targeting tumor-derived nano-vesicles therapeutically. In a 2012 publication in the prestigious journal Nature Medicine, Dr. David Lynden's group at Weill Cornell Medical College and their colleagues reported that melanoma tumors release exosomes that condition metastatic sites for growth of tumors and their supporting blood vessels3. This publication also identifies a correlation between high exosome concentrations in circulation with advanced disease and poor prognosis of patients. This knowledge reinforces the concept that a strategy for eliminating circulating exosomes could be beneficial for addressing metastatic disease.
A pivotal publication by Dr. Joshua Hood and colleagues at Washington University School of Medicine showed that melanoma exosomes migrate to lymph nodes and alter the biochemical milieu to allow lodging of cancer cells in the establishment of metastatic foci4. Once again, this study suggests that systemic clearance of melanoma exosomes could interrupt the "messenger system" underlying metastasis. Along these same lines, a study by Parolini and colleagues in The Journal of Biological Chemistry demonstrated that melanoma exosomes serve as delivery vehicles for spreading malignant proteins from high aggressive metastatic cells to less aggressive cancer cells5.This article raises the concept that exosomes from a primary tumor can transfer their cargo to distant organs, thereby allowing the malignancy to spread.
Experiments have also demonstrated that the functions of immune cells are impaired by melanoma exosomes6. Since the immune system is responsible for recognizing and destroying cancer cells, exosomes thereby manipulate immunity to allow tumors to grow unchecked. Additionally, since immunotherapy is administered to bolster the patient's endogenous immune response, melanoma exosomes impair the effectiveness of these treatments. On this basis, a device strategy for removal of circulating exosomes could be implemented to reverse immune dysfunction in order to improve the effectiveness of standard of care treatments against metastatic melanoma.
Given these recent scientific developments that reveal broad tumor growth promoting and immune inhibitory effects of melanoma exosomes, there is a strong impetus for moving forward with therapeutic targeting options, which do not exist to date. Clinical studies are needed to define the impact of exosomes in metastatic melanoma and to offer promising new treatment solutions that are urgently needed.
References
1 Logozzi M, De Milito A, Lugini L, Borghi M, Calabrò L, Spada M, Perdicchio M, Marino ML, Federici C, Iessi E, Brambilla D, Venturi G, Lozupone F, Santinami M, Huber V, Maio M, Rivoltini L, Fais S. High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. PLoS One. 2009;4(4):e5219.
2 http://www.cancer.org/cancer/ skincancer-melanoma/detailedguide/ melanoma-skin-cancer -survival-rates
3 Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med. 2012 Jun;18(6):883-91.
4 Hood JL, San RS, Wickline SA. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis. Cancer Res. 2011 Jun 1;71(11):3792-801.
5 Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, Coscia C, Iessi E, Logozzi M, Molinari A, Colone M, Tatti M, Sargiacomo M, Fais S. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem. 2009 Dec 4;284(49):34211-22.
6 Marton A, Vizler C, Kusz E, Temesfoi V, Szathmary Z, Nagy K, Szegletes Z, Varo G, Siklos L, Katona RL, Tubak V, Howard OM, Duda E, Minarovits J, Nagy K, Buzas K. Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro. ImmunolLett. 2012 Nov;148(1):34-8.
About Aethlon Medical
The Aethlon Medical mission is to create innovative medical devices that address unmet medical needs in cancer, infectious disease, and other life-threatening conditions. Our Aethlon ADAPT™ System is a revenue-stage technology platform that provides the basis for a new class of therapeutics that target the selective removal of disease enabling particles from the entire circulatory system. The Aethlon ADAPT™ product pipeline includes the Aethlon Hemopurifier® to address infectious disease and cancer; HER2osome™ to target HER2+ breast cancer, and a medical device being developed under a contract with DARPA that would reduce the incidence of sepsis in combat-injured soldiers and civilians. For more information, please visit www.aethlonmedical.com.
Certain statements herein may be forward-looking and involve risks and uncertainties. Such forward-looking statements involve assumptions, known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Aethlon Medical, Inc. to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such potential risks and uncertainties include, without limitation, that the company can successfully protect its intellectual property, that removal of exosomes from the human body will impact or lead to successful treatment of cancer, or that exosomes are the cause of tumor growth and progression, that the FDA will not approve the initiation of the Company's clinical programs or provide market clearance of the company's products, future human studies whether revenue or non-revenue generating of the Aethlon ADAPT™ system or the Aethlon Hemopurifier® as an adjunct therapy to improve patient responsiveness to established cancer or hepatitis C therapies or as a standalone cancer or hepatitis C therapy, the Company's ability to raise capital when needed, the Company's ability to complete the development of its planned products, the Company's ability to manufacture its products either internally or through outside companies and provide its services, the impact of government regulations, patent protection on the Company's proprietary technology, product liability exposure, uncertainty of market acceptance, competition, technological change, and other risk factors. In such instances, actual results could differ materially as a result of a variety of factors, including the risks associated with the effect of changing economic conditions and other risk factors detailed in the Company's Securities and Exchange Commission filings. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.
Contacts:
James A. Joyce
Chairman and CEO
858.459.7800 x301
jj@aethlonmedical.com
Jim Frakes
Chief Financial Officer
858.459.7800 x300
jfrakes@aethlonmedical.com
Marc Robins
877.276.2467
mr@aethlonmedical.com
Published at Investorideas.com Newswire
More info on AEMD at Investorideas.com Visit: http://www.investorideas.com/CO/AEMD/
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Automotive Stock Alert; MWW Automotive (OTCQB: MWWC) Gains 110% in Morning Trading

Point Roberts, WA - December 6, 2012 (Investorideas.com newswire) Investorideas.com staff: Investorideas.com, an investor research portal specializing in sector research for independent investors, including automotive stocks, issues a trading alert for MWW Automotive Group (OTCQB: MWWC). The stock is trading at $0.0011, up 0.0006 or 120.00% as of 11:01AM EST on just under 4 Million shares.

The Company recently reported an agreement with G.S.I selecting MWW as its North American Finishing Supplier for their industrial product offerings in North America with multiple year painting and fulfillment programs for Industrial and Agricultural Equipment components.
G.S.I. is a global Tier One supplier of complete turnkey products and systems for the global automotive and industrial markets, based in Chicago. G.S.I. primary markets include agricultural, construction, automotive and electrical equipment and machinery. Major clients include, among others, AGCO, Argo Tractors, Carraro, Case New Holland, Caterpillar, Class, Massey Ferguson and Shanghai New Holland.
Full news: http://www.investorideas.com/CO/MWWA/news/2012/11291.asp
About MWW Automotive Group (OTCQB: MWWC)
The MWW Automotive Group (MWWC) is headquartered in Howell, Michigan, with a "Class A" manufacturing and logistics facility in Baroda, Michigan for the production of high quality OE automotive and industrial products. MWW delivers its products and "Class A" painting, assembly and logistics services directly to major US and Foreign automobile manufacturers' Vehicle Processing Centers (VPC) and/or assembly lines in North America. MWW's industrial products are delivered directly to the industrial manufacturers for installation in their facilities. MWW provides substantial added value to the sale of vehicles and industrial products for leading international automobile and industrial manufacturers such as Toyota, BMW, Chevrolet, Hyundai, Kia Motors, MAZDA, GM, Ford, and their strategic partners ROUSH Performance and Polytec.
For more information please visit www.mwwautomotive.com
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Agriculture Stocks: The Global Growth for Stevia; Sunwin Stevia's (OTCQB:SUWN) Distribution Partner WILD Flavors Sees Positive Results One Year After the EU Grants Approval

POINT ROBERTS, WA - December 6, 2012 (Investorideas.com Newswire) Investorideas.com, an investor research portal specializing in sector research for independent investors, issues a snapshot for the global stevia market and stocks within the sector, including Sunwin Stevia International, Inc. (OTCQB:SUWN).

Recently President of the International Stevia Council (ISC) said Stevia had fundamentally changed the sweetener market. Lauren Bandy, Ingredients Research Analyst with Euromonitor International told Investorideas.com, "There is no doubt that stevia has shaken the high intensity sweeteners market, most of all because it is sourced naturally. This puts it at a great advantage to other high intensity sweeteners such as aspartame and sucralose, which are chemically derived. It still is relatively expensive compared to other sweeteners such as sugar, and only represents 2% of the high intensity sweeteners market in volume terms in 2012, although this has doubled since 2011."
She went on to note, "I think stevia manufacturers will continue to target large, multinational brands, as they are at the moment. Stevia offers food and beverage manufacturers a way to reduce the sugar content of their products in a more natural way. Health and wellness is a key trend in the food and beverage sector and stevia is perfectly positioned to capitalize on the growth of the better-for-you market."
According to Foodingredientsfirst.com, "One year after the European Union granted approval for steviolglycosides to be marketed, WILD Flavors ( Sunwin Stevia's (OTCQB:SUWN) distribution partner) has noted positive interim results. The great-taste expert has worked with customers to create a number of stevia-sweetened products that have been market successes — everything from beverages to candies."
Sunwin (OTCQB:SUWN) began an expansion production project in April 2012 in anticipation of an improvement in demand in the coming years as the use of stevia as a healthy low calorie sweetener continues to increase across the globe. Sunwin has begun trial production of its new lines and anticipates its added production capabilities to be fully operational in the first quarter of calendar 2013.
Lauren Bandy reports " Western Europe is the world's largest packaged food market in value terms and was worth just under US$600 billion in 2012. Since its EU approval, stevia suppliers have really been tapping into this lucrative market. Euromonitor shows that stevia consumption in Western Europe in volume terms is forecast to grow by 50% over 2012-2016, from 190 tonnes in 2012 to nearly 300 tonnes in 2016.
A number of key brands have since launched stevia containing products in Europe - for example in France and Ireland, the Coca Cola Company has reformulated Sprite using stevia, reducing sugar content by 30%."
Health Canada just gave stevia the okay to become an ingredient in mainstream food and beverages. PureCircle Limited (LSE:PURE.L) one of the world's leading producer of high purity stevia ingredients for the global food and beverage industry and GLG Life Tech (GLGLF) say they have been ramping up for the anticipated Canadian approval according to a recent article in foodnavigator-usa.com.
In terms of potential obstacles Lauren Bandy said there are a few to overcome. " India is the most significant market and the last of the BRIC countries not to permit stevia as a sweetening ingredient. Countries in Latin America and Asia Pacific - which also have the fastest growing packaged food and soft drink markets globally - have been using stevia for many years.
The other hurdle to stevia's global success is the controversy surrounding its natural status, a debate which is stronger in Europe than America. Because stevia has an E number (E960) and because steviol glycosides - the sweet compounds - have to be extracted from the plant and processed, some consumers consider stevia as ‘just another additive'.
Stevia's bitter aftertaste also remains an obstacle, although this is a highly researched and rapidly developing area and is unlikely to affect its market penetration; Euromonitor forecast that stevia will have an annual growth rate of 23% globally over 2011-2016, in volume terms."
To address any concerns with taste, WILD's Sunwin Stevia™ (OTCQB:SUWN) brand provides beverage manufacturers one-source solutions: high-quality Stevia extracts in varying Reb Alevels plus WILD's natural Taste Optimization Technology.
The natural Taste Optimization Technology eliminates the characteristic licorice nuance and partly bitter aftertaste of Stevia. Manufacturers can therefore create delicious tasting, naturally sweetened products with the natural sweetening system Stevia, ranging from near waters, tea drinks or carbonated soft drinks, to fruit juice-containing drinks and beer mixes. WILD's Sunwin Stevia™ allows for great-tasting calorie-reduced, low calorie or calorie-free varieties, according to customer demands and market requirements.
About WILD Flavors GmbH,
WILD Flavors GmbH, based in Zug, Switzerland, is one of the world's leading privately-owned manufacturers of natural ingredients for the food and beverage industry. WILD Flavors provides specific flavors, colors, and ingredients as well as innovative and great tasting concepts through application expertise and technological advancements. www.wildflavors.com or www.wild.de
About Sunwin Stevia International, Inc. (OTCQB: SUWN)
Sunwin Stevia International, Inc. engages in the areas of zero calorie, all natural sweeteners (Sunwin Stevia™ Extracts). As an industry leader in agricultural processing, Sunwin has built an integrated global firm with the sourcing and production capabilities to meet the needs of consumers throughout the world. For more info about Sunwin, please visit http://www.sunwininternational.com
Contact:
SUWN contact: Dore Perler
U.S. Representative
954-232-5363
ir@sunwininternational.com
Lauren Bandy works as Ingredients Research Analyst with Euromonitor International. She directly contributes to the content and quality of Euromonitor International's Food & Drinks Ingredients research, with a special focus on health ingredients, sweeteners, and cocoa ingredients. Lauren monitors key industry trends and forecasts and is responsible for the writing of articles and analysis, which provide detailed insight into the state of the industry. In her current role at Euromonitor International, Lauren uses her expert knowledge of the ingredients industry to create quality data and insight on a range of topics including key market trends and opportunities, regulation and innovative ingredients.
Lauren holds a degree in Nutrition from King's College, London.
Research more Agriculture and stevia stocks at Investorideas.com
http://www.investorideas.com/MSS/Arg_Stock_List.asp
Article source: http://www.foodingredientsfirst.com/news/Wild-Sees-Positive-Interim-Results-One-Year-After-Stevia-Approval.html
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More Sunwin info at Investorideas.com http://www.investorideas.com/CO/SUWN/
Disclaimer/ Disclosure: The Investorideas.com is a third party publisher of news and research Our sites do not make recommendations, but offer information portals to research news, articles, stock lists and recent research. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. This site is currently compensated by featured companies, news submissions and online advertising. Disclosure: Investorideas.com is compensated by China Direct on behalf of SUWN, averaging four thousand two hundred per week for news publication, dissemination and profile on Invesotrideas.com , its affiliate news and email sites including ir app on Running Bull http://www.investorideas.com/About/Disclaimer.asp
BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894
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Investorideas.com; helping public companies stay out of the red and investors see a little green for Holidays!

Point Roberts, WA - December 5, 2012 (www.investorideas.com newswire) Investorideas.com, an investor research portal specializing in sector research for independent investors issues a holiday special limited offer for publicly traded companies on and investors trading the TSX, OTC, NASDAQ and ASX markets.

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BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894
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Global Growth for Stevia; WILD Flavors, Sunwin Stevia's (OTCQB:SUWN) Distribution Partner, Sees Results One year after the European Union Grants Approval

Point Roberts, WA - December 5, 2012 (Investorideas.com Newswire) Investorideas.com, an investor research portal specializing in sector research for independent investors issues a sector snapshot on the stevia market and stevia stocks including Sunwin Stevia International, Inc. (OTCQB: SUWN), following recent news of Health Canada's approval for stevia as an ingredient in food and beverages.

Recently President of the International Stevia Council (ISC) said Stevia had fundamentally changed the sweetener market. Lauren Bandy, Ingredients Research Analyst with Euromonitor International told Investorideas.com, "There is no doubt that stevia has shaken the high intensity sweeteners market, most of all because it is sourced naturally. This puts it at a great advantage to other high intensity sweeteners such as aspartame and sucralose, which are chemically derived. It still is relatively expensive compared to other sweeteners such as sugar, and only represents 2% of the high intensity sweeteners market in volume terms in 2012, although this has doubled since 2011."
She went on to note, "I think stevia manufacturers will continue to target large, multinational brands, as they are at the moment. Stevia offers food and beverage manufacturers a way to reduce the sugar content of their products in a more natural way. Health and wellness is a key trend in the food and beverage sector and stevia is perfectly positioned to capitalize on the growth of the better-for-you market."
According to Foodingredientsfirst.com, "One year after the European Union granted approval for steviolglycosides to be marketed, WILD Flavors ( Sunwin Stevia's (OTCQB:SUWN) distribution partner) has noted positive interim results. The great-taste expert has worked with customers to create a number of stevia-sweetened products that have been market successes — everything from beverages to candies."
Sunwin (OTCQB:SUWN) began an expansion production project in April 2012 in anticipation of an improvement in demand in the coming years as the use of stevia as a healthy low calorie sweetener continues to increase across the globe. Sunwin has begun trial production of its new lines and anticipates its added production capabilities to be fully operational in the first quarter of calendar 2013.
Lauren Bandy reports " Western Europe is the world's largest packaged food market in value terms and was worth just under US$600 billion in 2012. Since its EU approval, stevia suppliers have really been tapping into this lucrative market. Euromonitor shows that stevia consumption in Western Europe in volume terms is forecast to grow by 50% over 2012-2016, from 190 tonnes in 2012 to nearly 300 tonnes in 2016.
A number of key brands have since launched stevia containing products in Europe - for example in France and Ireland, the Coca Cola Company has reformulated Sprite using stevia, reducing sugar content by 30%."
Health Canada just gave stevia the okay to become an ingredient in mainstream food and beverages. PureCircle Limited (LSE:PURE.L) one of the world's leading producer of high purity stevia ingredients for the global food and beverage industry and GLG Life Tech (GLGLF) say they have been ramping up for the anticipated Canadian approval according to a recent article in foodnavigator-usa.com.
In terms of potential obstacles Lauren Bandy said there are a few to overcome. " India is the most significant market and the last of the BRIC countries not to permit stevia as a sweetening ingredient. Countries in Latin America and Asia Pacific - which also have the fastest growing packaged food and soft drink markets globally - have been using stevia for many years.
The other hurdle to stevia's global success is the controversy surrounding its natural status, a debate which is stronger in Europe than America. Because stevia has an E number (E960) and because steviol glycosides - the sweet compounds - have to be extracted from the plant and processed, some consumers consider stevia as ‘just another additive'.
Stevia's bitter aftertaste also remains an obstacle, although this is a highly researched and rapidly developing area and is unlikely to affect its market penetration; Euromonitor forecast that stevia will have an annual growth rate of 23% globally over 2011-2016, in volume terms."
To address any concerns with taste, WILD's Sunwin Stevia™ (OTCQB:SUWN) brand provides beverage manufacturers one-source solutions: high-quality Stevia extracts in varying Reb Alevels plus WILD's natural Taste Optimization Technology.
The natural Taste Optimization Technology eliminates the characteristic licorice nuance and partly bitter aftertaste of Stevia. Manufacturers can therefore create delicious tasting, naturally sweetened products with the natural sweetening system Stevia, ranging from near waters, tea drinks or carbonated soft drinks, to fruit juice-containing drinks and beer mixes. WILD's Sunwin Stevia™ allows for great-tasting calorie-reduced, low calorie or calorie-free varieties, according to customer demands and market requirements.
About WILD Flavors GmbH,
WILD Flavors GmbH, based in Zug, Switzerland, is one of the world's leading privately-owned manufacturers of natural ingredients for the food and beverage industry. WILD Flavors provides specific flavors, colors, and ingredients as well as innovative and great tasting concepts through application expertise and technological advancements. www.wildflavors.com or www.wild.de
About Sunwin Stevia International, Inc. (OTCQB: SUWN)
Sunwin Stevia International, Inc. engages in the areas of zero calorie, all natural sweeteners (Sunwin Stevia™ Extracts). As an industry leader in agricultural processing, Sunwin has built an integrated global firm with the sourcing and production capabilities to meet the needs of consumers throughout the world. For more info about Sunwin, please visit http://www.sunwininternational.com
Contact:
SUWN contact: Dore Perler
U.S. Representative
954-232-5363
ir@sunwininternational.com
Lauren Bandy works as Ingredients Research Analyst with Euromonitor International. She directly contributes to the content and quality of Euromonitor International's Food & Drinks Ingredients research, with a special focus on health ingredients, sweeteners, and cocoa ingredients. Lauren monitors key industry trends and forecasts and is responsible for the writing of articles and analysis, which provide detailed insight into the state of the industry. In her current role at Euromonitor International, Lauren uses her expert knowledge of the ingredients industry to create quality data and insight on a range of topics including key market trends and opportunities, regulation and innovative ingredients.
Lauren holds a degree in Nutrition from King's College, London.
Research more Agriculture and stevia stocks at Investorideas.com
http://www.investorideas.com/MSS/Arg_Stock_List.asp
Article source: http://www.foodingredientsfirst.com/news/Wild-Sees-Positive-Interim-Results-One-Year-After-Stevia-Approval.html
About InvestorIdeas.com:
InvestorIdeas.com is a leader in investor stock research by sector, featuring stock news, commentary and trading alerts in leading sectors including biotech, tech, mining, energy, water, renewable energy, beverage stocks and more .
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Mining Stock News: SilverCrest (TSX.V: SVL) (NYSE MKT: SVLC) Announces Grant of Stock Options

VANCOUVER, BRITISH COLUMBIA - December 5, 2012 (Investorideas.com Mining Stocks Newswire) SilverCrest Mines Inc. (TSX.V:SVL) ( NYSE MKT: SVLC) (CW5.F) (the "Company") announces the grant of stock options to directors, officers, employees and consultants to purchase an aggregate of 1,760,000 common shares of the Company at an exercise price of $2.60 per share for a term of 5 years. One quarter of these options vest on the date of grant and a further one-quarter will vest every six months thereafter.

SilverCrest Mines Inc. (TSX-V: SVL; NYSE MKT: SVLC) is a Canadian precious metals producer headquartered in Vancouver, BC. SilverCrest's flagship property is the 100%-owned Santa Elena Mine, located 150 km northeast of Hermosillo, near Banamichi in the State of Sonora, Mexico. The mine is a high-grade, epithermal gold and silver producer, with an estimated life of mine cash cost of US$8 per ounce of silver equivalent (55:1 Ag:Au). SilverCrest anticipates that the 2,500 tonnes per day facility should recover approximately 4,805,000 ounces of silver and 179,000 ounces of gold over the 6.5 year life of the open pit phase of the Santa Elena Mine. A three year expansion plan is underway to double metals production at the Santa Elena Mine and exploration programs are rapidly advancing the definition of a large polymetallic deposit at the La Joya property in Durango State.
FORWARD-LOOKING STATEMENTS
This news release contains "forward-looking statements" within the meaning of Canadian securities legislation and the United States Securities Litigation Reform Act of 1995. Such forward-looking statements concern the Company's anticipated results and developments in the Company's operations in future periods, planned exploration and development of its properties, plans related to its business and other matters that may occur in the future. These statements relate to analyses and other information that are based on expectations of future performance, including silver and gold production and planned work programs. Statements concerning reserves and mineral resource estimates may also constitute forward-looking statements to the extent that they involve estimates of the mineralization that will be encountered if the property is developed and, in the case of mineral reserves, such statements reflect the conclusion based on certain assumptions that the mineral deposit can be economically exploited.
Forward-looking statements are subject to a variety of known and unknown risks, uncertainties and other factors which could cause actual events or results to differ from those expressed or implied by the forward-looking statements, including, without limitation: risks related to precious and base metal price fluctuations; risks related to fluctuations in the currency markets (particularly the Mexican peso, Canadian dollar and United States dollar); risks related to the inherently dangerous activity of mining, including conditions or events beyond our control, and operating or technical difficulties in mineral exploration, development and mining activities; uncertainty in the Company's ability to raise financing and fund the exploration and development of its mineral properties; uncertainty as to actual capital costs, operating costs, production and economic returns, and uncertainty that development activities will result in profitable mining operations; risks related to reserves and mineral resource figures being estimates based on interpretations and assumptions which may result in less mineral production under actual conditions than is currently estimated and to diminishing quantities or grades of mineral reserves as properties are mined; risks related to governmental regulations and obtaining necessary licenses and permits; risks related to the business being subject to environmental laws and regulations which may increase costs of doing business and restrict our operations; risks related to mineral properties being subject to prior unregistered agreements, transfers, or claims and other defects in title; risks relating to inadequate insurance or inability to obtain insurance; risks related to potential litigation; risks related to the global economy; risks related to the Company's status as a foreign private issuer in the United States; risks related to all of the Company's properties being located in Mexico and El Salvador, including political, economic, social and regulatory instability; and risks related to officers and directors becoming associated with other natural resource companies which may give rise to conflicts of interests. Should one or more of these risks and uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described in the forward-looking statements. The Company's forward-looking statements are based on beliefs, expectations and opinions of management on the date the statements are made. For the reasons set forth above, investors should not place undue reliance on forward-looking statements.
The information provided in this news release is not intended to be a comprehensive review of all matters and developments concerning the Company. It should be read in conjunction with all other disclosure documents of the Company. The information contained herein is not a substitute for detailed investigation or analysis. No securities commission or regulatory authority has reviewed the accuracy or adequacy of the information presented.
J. Scott Drever, President
SILVERCREST MINES INC.
Contact:
SilverCrest Mines Inc.
Fred Cooper
(604) 694-1730 ext. 108
Toll Free: 1-866-691-1730
(604) 694-1761 (FAX)
info@silvercrestmines.com
www.silvercrestmines.com
570 Granville Street, Suite 501
Vancouver, British Columbia V6C 3P1
Published at Investorideas.com Newswire
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BC Residents and Investor Disclaimer : Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894

Stevia Stock Alert: Sunwin Stevia (OTCQB: SUWN) Expands Production Facility: Health Canada Approval and EU Approval Step Up Global Demand For Stevia

Point Roberts, WA - December 4, 2012 (Investorideas.com Newswire) Investorideas.com staff: Investorideas.com, an investor research portal specializing in sector research for independent investors issues a news and trading alert for agriculture stevia stock, Sunwin Stevia International, Inc. (OTCQB:SUWN). Yesterday the Company announced the installation of new High tech production lines to expand stevia production capacity to 1,300 Metric Tons.

The stock moved to .$0.30 in Tuesday morning trading following the news, making recent new highs.
Stevia made headlines as Health Canada approved stevia November 30th as an additive to food and beverages. FoodIngrediantsfirst.com reported November 28 th referencing Sunwin's . (OTCQB:SUWN) marketing partner, WILD Flavors, “One year after the European Union granted approval for steviolglycosides to be marketed, WILD has noted positive interim results. The great-taste expert has worked with customers to create a number of stevia-sweetened products that have been market successes -- everything from beverages to candies.”
Sunwin began its expansion project in April 2012 in anticipation of an improvement in demand in the coming years as the use of stevia as a healthy low calorie sweetener continues to increase across the globe. Sunwin has begun trial production of its new lines and anticipates its added production capabilities to be fully operational in the first quarter of calendar 2013.
The completion of this high tech expansion of its production facilities brings Sunwin's total bulk stevia production capacity to 1,300 metric tons, including 500 metric tons of high grade stevioside products (Rabaudioside 60, 80, 95, 98, and 99) and 500 metric tons of steviosin which is a stevioside extract used in the pharmaceutical industry.
Sunwin's new stevioside extraction line uses a state of the art crystallization process that substantially reduces the production time while increasing product yield. Sunwin believes this process will lead to a substantial reduction in overall processing costs as utilization rates increase. In addition, Sunwin's facilities are now capable of producing 500 metric tons of stevioside in granular and tablet forms on an annual basis. Demand for stevia in these forms has been increasing and management believes Sunwin is now poised to capitalize on this industry trend.
Article source: http://www.foodingredientsfirst.com/news/Wild-Sees-Positive-Interim-Results-One-Year-After-Stevia-Approval.html
About Sunwin Stevia International, Inc.
Sunwin Stevia International, Inc. engages in the areas of zero calorie, all natural sweeteners (Sunwin Stevia™ Extracts). As an industry leader in agricultural processing, Sunwin has built an integrated global firm with the sourcing and production capabilities to meet the needs of consumers throughout the world. For more info about Sunwin, please visit http://www.sunwininternational.com
About WILD Flavors GmbH,
WILD Flavors GmbH, based in Zug, Switzerland, is one of the world's leading privately-owned manufacturers of natural ingredients for the food and beverage industry. WILD Flavors provides specific flavors, colors, and ingredients as well as innovative and great tasting concepts through application expertise and technological advancements. For more information about WILD, please visit: www.wildflavors.com or www.wild.de.
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BC Residents and Investor Disclaimer: Effective September 15 2008 - all BC investors should review all OTC and Pink sheet listed companies for adherence in new disclosure filings and filing appropriate documents with Sedar. Read for more info: http://www.bcsc.bc.ca/release.aspx?id=6894
800-665-0411 - Source - www.Investorideas.com

Energy Stock News; EFL Overseas Inc. (OTCBB: EFLO) Reports Acquisition of Additional Interest at Kotaneelee and Reserves and Resources Update

HOUSTON, TEXAS - December 4, 2012 (Investorideas.com energy newswire) EFL Overseas Inc. (OTCBB:EFLO) is pleased to announce the acquisition of additional working interests in the Kotaneelee gas property and the results of independent reserves and resources evaluations (NI-51-101 compliant).

ACQUISITION
Effective October 17, 2012, EFLO acquired a 30.664% interest in the Liard basin gas field and facilities located in the Kotaneelee Area, Yukon Territory, Canada (the "Assets") from Nahanni Energy Inc. and certain of its wholly owned subsidiaries ("Nahanni"). The Nahanni purchase follows EFLO's earlier acquisition of Devon Canada's interest (generally a working interest of 22.989%, with a working interest of 69.337% in one gas well) in the Assets. Upon closing the Nahanni purchase, EFLO became the largest interest holder in the Kotaneelee with a general interest of 53.65% and a working interest of 100% in one gas well.
"Our acquisition of the additional interest at Kotaneelee provides us with a controlling position in this exciting project", stated EFLO Chairman Henry Aldorf. "Increasing our working interest to approx. 54% allows us to drive forward development plans and offers our shareholders greater potential upside."
"With the closing of the Nahanni acquisition, we are focused on actively pursuing additional interests at Kotaneelee and the surrounding area," added EFLO Chief Executive Officer Keith Macdonald. "The larger asset base will be helpful as we evaluate our future market opportunities in the Pacific Rim, North America and the Yukon."
The Assets include 30,542 acres of land, a gas dehydration plant (capacity: 70 MMcf/d), one water disposal well (capacity: 6,000 bbls/d), one well temporarily shut-in for plant maintenance and two suspended gas wells, flarestack, storage tanks, airstrip, roads, gathering systems, geological data, equipment, and other transportation and camp infrastructure.
As consideration for the Assets, EFLO paid Nahanni US$132,600 in cash (representing closing consideration of Cdn$400,000 less certain pre-closing liabilities settled by EFLO), and 1,614,767 shares of one of its subsidiaries, which are exchangeable on a one-for-one basis for shares of EFLO's common stock (valued at Cdn$4,100,000; US$4,190,610). In addition, EFLO indemnified Nahanni against its portion of the abandonment, reclamation and environmental liabilities associated with the Assets. EFLO intends to undertake an active development and exploration program, which is expected to defer these potential liabilities into the future.
EFLO continues to pursue the acquisition of additional working interests in the Assets.
RESERVES
The following reports certain pro forma reserve information, after giving effect to both the Devon and Nahanni acquisitions, based on an independent assessments by AJM Deloitte ("AJM") of dated effective June 30, 2012 using forecast prices and costs (the "EFLO AJM Reserve Reports"). AJM prepared separate reports for the Devon and Nahanni acquired working interests. The numbers presented below reflect an aggregation of the two reports. The EFLO AJM Reserve Reports were prepared in accordance with definitions, standards and procedures contained in the Canadian Oil and Gas Evaluation Handbook ("COGE Handbook") and National Instrument 51-101 Standards of Disclosure for Oil and Gas Activities ("NI 51-101"). In addition reserve information required under NI 51-101 and effective for the EFLO's fiscal year ended August 31, 2012 will be included in NI 51-101 forms which will be filed in connection with EFLO's financial statements as at and for the year ended August 31, 2012. Such reserve information was filed on Sedar on November 29, 2012 and gives effect only to the Company's reserves resulting from the Devon acquisition, as the Nahanni acquisition occurred subsequent to August 31, 2012. The differences between Devon related reserves and net present values reported in the June 30 report and the August 31 report are not material.
Gas prices for the report were based on delivery and sale at Station 2 in British Columbia. The EFLO AJM Reserve Reports base case forecast effective June 30, 2012 is as follows: 2012 - $2.00; 2013 - $2.95; 2014 - $3.55; 2015 - $3.95; 2016 - $4.35; 2017 - $4.80; 2018 - $5.35; 2019 - $5.80; 2020 - $6.50; and thereafter escalated at 2% per annum. Prices are in Canadian dollars per Mcf.
SUMMARY OF RESOURCES
The following reports certain pro forma resource information, based on an independent assessment by AJM dated effective June 30, 2012 using forecast prices and costs (the "EFLO AJM Resource Report"). The EFLO AJM Resource Report was prepared in accordance with definitions, standards and procedures contained in the COGE Handbook and NI 51-101.
The AJM Resource report evanuated the resources on EFLO acreage on gross terms and did not consider working interest. AJM evaluated the lands to assess the resource potential for the Middle Devonian Shales designated as Lower Black Shale (Muskwa/Evie), Middle Shale (Fort Simpson), and Upper Shale (Kotcho/Exshaw) as well as the potential for expansion of resource for the Nahanni on the producing East Flank. The results are summarized as follows, adjusted by management to reflect EFLO's 53.65% interest in the evaluated lands after giving effect to the Devon and Nahanni acquisitions.
Summary of Resources on EFL Overseas Lands (1)
Kotaneelee, Yukon Territory
The following represents the total for the low, best and high cases as evaluated for the Shales.
In addition, AJM has evaluated a Nahanni prospect on the West Flank.
NOTICE REGARDING PRESENTATION OF THE COMPANY''S RESERVE AND CONTINGENT RESOURCE INFORMATION
The determination of reserves and resources involves the preparation of estimates that have an inherent degree of associated uncertainty. The estimation and classification of reserves and resources requires the application of professional judgment combined with geological and engineering knowledge to assess whether or not specific reserve or resource classification criteria have been satisfied. Knowledge of concepts including uncertainty and risk, probability, statistics and deterministic and probabilistic estimation methods is required to properly use and apply reserve and resource definitions.
Disclosure in this document of reserves and resources is presented in accordance with Canadian securities laws. The United States Securities and Exchange Commission (the "SEC") generally permits U.S. reporting oil and gas companies, in their filings with the SEC, to disclose only proved, probable and possible reserves and production, net of royalties and interests of others. The Company uses certain terms in this document, such as resources or contingent resources that the SEC's rules would prohibit a U.S. company from including in filings with the SEC. The SEC generally does not permit U.S. companies to disclose net present value of future net revenue from reserves based on forecast prices and costs. Canadian securities laws permit, among other things, the presentation of certain categories of resources and the disclosure of production on a gross basis before deducting royalties. Unless noted otherwise, all disclosures of reserves and resources in this document are made on a gross basis using forecast price and cost assumptions.
In this news release:
"gross" means:
(a) in relation to the Company's interest in production or reserves, its working interest share before deduction of royalties;
(b) in relation to wells, the total number of wells in which the Company has an interest; and
(c) in relation to properties, the total area of properties in which the Company has an interest.
"net" means:
(a) in relation to the Company's interest in production or reserves, its working interest share after deduction of royalty obligations;
(b) in relation to the Company's interest in wells, the number of wells obtained by aggregating the Company's working interest in each of its gross wells; and
(c) in relation to the Company's interest in a property, the total area of properties in which the Company has an interest multiplied by the working interest owned by the Company.
All evaluations of future revenue are after the deduction of royalties, development costs, production costs and well abandonment costs but before consideration of indirect costs such as administrative, overhead and other miscellaneous expenses.
Disclosure of Reserves
The reserves estimates and related estimates of net present values presented in this document were prepared to comply with Canadian reserves disclosure standards and reserves definitions as set out in NI 51-101 and the COGE Handbook prepared jointly by The Society of Petroleum Evaluation Engineers (Calgary Chapter) and the Canadian Institute of Mining, Metallurgy & Petroleum (Petroleum Society).
Reserves are estimated remaining quantities of oil and natural gas and related substances anticipated to be recoverable from known accumulations, from a given date forward, based on:

• analysis of drilling, geological, geophysical and engineering data;
• the use of established technology; and
• specified economic conditions, which are generally accepted as being reasonable.

Reserves are classified according to the degree of certainty associated with the estimates:

• Proved reserves are those reserves that can be estimated with a high degree of certainty to be recoverable. It is likely that the actual remaining quantities recovered will exceed the estimated proved reserves;
• Probable reserves are those additional reserves that are less certain to be recovered than proved reserves. It is equally likely that the actual remaining quantities recovered will be greater or less than the sum of the estimated proved plus probable reserves; and
• Possible reserves are those additional reserves that are less certain to be recovered than probable reserves. It is unlikely that the actual remaining quantities recovered will exceed the sum of the estimated proved plus probable plus possible reserves.

Each of the reserves categories (proved, probable and possible) may be divided into developed and undeveloped categories:

• Developed reserves are those reserves that are expected to be recovered from existing wells and installed facilities or, if facilities have not been installed, that would involve a low expenditure (for example, when compared to the cost of drilling a well) to put the reserves on production. The developed category may be subdivided into producing and non-producing.
• Developed producing reserves are those reserves that are expected to be recovered from completion intervals open at the time of the estimate. These reserves may be currently producing or, if shut-in, they must have previously been on production, and the date of resumption of production must be known with reasonable certainty.
• Developed non-producing reserves are those reserves that either have not been on production, or have previously been on production, but are shut-in, and the date of resumption of production is unknown.
• Undeveloped reserves are those reserves expected to be recovered from known accumulations where a significant expenditure (for example, when compared to the cost of drilling a well) is required to render them capable of production. They must fully meet the requirements of the reserves classification (proved, probable, possible) to which they are assigned.

In multi-well pools it may be appropriate to allocate total pool reserves between the developed and undeveloped categories or to subdivide the developed reserves for the pool between developed producing and developed non-producing. This allocation should be based on the estimator's assessment as to the reserves that will be recovered from specific wells, facilities and completion intervals in the pool and their respective development and production status.
The qualitative certainty levels referred to in the definitions above are applicable to individual reserves entities (which refers to the lowest level at which reserves calculations are performed) and to reported reserves (which refers to the highest level or the sum of individual entity estimates for which reserves estimates are presented). Reported reserves should target the following levels of certainty under a specific set of economic conditions:

• at least a 90 percent probability that the quantities actually recovered will equal or exceed the estimated proved reserves;
• at least a 50 percent probability that the quantities actually recovered will equal or exceed the sum of the estimated proved plus probable reserves; and
• at least a 10 percent probability that the quantities actually recovered will equal or exceed the sum of the estimated proved plus probable plus possible reserves.

Additional clarification for the classification of reserves and the certainty levels associated with reserves estimates is provided in the COGE Handbook.
Disclosure of Resources
In this news release, the Company also refers to estimates of "contingent resources". These estimates represent the best estimate of the contingent resources attributed to the Company's interest, are not classified or recognized as reserves, and are in addition to the Company's disclosed reserve volumes.
Contingent resources are those quantities of petroleum estimated, as of a given date, to be potentially recoverable from known accumulations using established technology or technology under development, but which are not currently considered to be commercially recoverable due to one or more contingencies. Contingencies may include factors such as economic, legal, environmental, political, and regulatory matters, or a lack of markets. It is also appropriate to classify as contingent resources the estimated discovered recoverable quantities associated with a project in the early evaluation stage. There is no certainty that it will be commercially viable to produce any portion of the contingent resources and the estimated future net revenues do not necessarily represent the fair market value of such contingent resources.
The Company's resources classified as contingent resources, rather than as reserves, are so classified pending the need for further facility design, preparation of firm development plans and regulatory applications (including associated reservoir studies and delineation drilling) and corporate approvals to proceed with development.
When evaluating contingent resources, the following mutually exclusive categories are recommended in the COGE Handbook:

• Low Estimate: This is considered to be a conservative estimate of the quantity that will actually be recovered. It is likely that the actual remaining quantities recovered will exceed the low estimate. If probabilistic methods are used, there should be at least 90 percent probability that the quantities actually recovered will equal or exceed the low estimate.
• Best Estimate: This is considered to be the best estimate of the quantity that will actually be recovered. It is equally likely that the actual remaining quantities recovered will be greater or less than the best estimate. If probabilistic methods are used, there should be at least a 50 percent probability that the quantity actually recovered will equal or exceed the best estimate.
• High Estimate: This is considered to be an optimistic estimate of the quantity that will actually be recovered. It is unlikely that the actual remaining quantities recovered will exceed the high estimate. If probabilistic methods are used, there should be at least a 10 percent probability that the quantities actually recovered will equal or exceed the high estimate.

FORWARD-LOOKING STATEMENTS
This news release includes forward-looking statements, including but not limited to estimates of reserves and resources and the present value of revenues associated with such reserves and resources. Statements in this news release relating to reserves and resources involve the implied assessment, based on certain estimates and assumptions, that the described reserves and resources, as the case may be, exist in the quantities predicted or estimated, and can be profitably produced in the future. There is no assurance that the forecast price and cost assumptions contained in the AJM reports will be realized and variances could be material. Other assumptions and qualifications relating to project schedules, costs and other matters are inherent in these estimates.
In addition, all statements other than statements of historical facts, included in this news release that address activities, events, or developments that the Company believes or anticipates will or may occur in the future are forward-looking statements, including but not limited to the Company's intent to pursue the acquisition of additional interest in the Kotaneelee property, the Company's planned exploration activities and the existence of potential opportunities in the Pacific Rim, North America and the Yukon. Such forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause the actual results, performance or achievements expressed or implied by such forward-looking statements. Such factors include general economic and business conditions, the ability to acquire and develop specific projects and reach commercially acceptable terms with counterparties, the ability to secure government and other third party approval, potential third party claims, the ability to fund operations, and other factors over which the Company has little or no control. The Company does not intend to update publicly any forward-looking statements, except as may be required by law. There can be no assurance that EFLO will be successful in completing the acquisition of additional interest(s) in the Kotaneelee properties or executing its planned exploration and development activities.
The contents of this news release should be considered in conjunction with the warnings and cautionary statement contained in the Company's public filings, which are accessible on SEDAR at www.sedar.com.
Definitions
In this news release: (i) Mcf means thousand cubic feet; (ii) Mcf/d means thousand cubic feet per day; (iii) MMcf means million cubic feet; (iv) MMcf/d means million cubic feet per day; (v) bbls means barrels; (vi) Mbbls means thousand barrels; (vii) MMbbls means million barrels; (viii) bbls/d means barrels per day; (ix) Bcf means billion cubic feet; (x) Mboe means thousand barrels of oil equivalent; (xi) MMboe means million barrels of oil equivalent; (xii) boe means barrels of oil equivalent; and (xiii) boe/d means barrels of oil equivalent per day.
Boe means barrel of oil equivalent on the basis of 1 boe to 6,000 cubic feet of natural gas. References to boe may be misleading, particularly if used in isolation. A boe conversion ratio of 1 boe for 6,000 cubic feet to natural gas is based on an energy equivalency conversion method primarily applicable at the burner tip and does not represent a value equivalency at the wellhead.
Contact:
EFL Overseas Inc.
Keith Macdonald
1 (403) 246-8443