Thursday, June 20, 2024

Follow the Money in Metals Recycling – (NASDAQ: $GWAV) (NYSE: $RIO) (NYSE: $ALB) (NYSE: $LZM) (OTCQX: $NGLOY) (OTC: $GLNCY) @GreenwaveGWAV @AngloAmerican @Glencore @LifezoneMetals @AlbemarleCorp

Follow the Money in Metals Recycling – (NASDAQ: $GWAV) (NYSE: $RIO) (NYSE: $ALB) (NYSE: $LZM) (OTCQX: $NGLOY) (OTC: $GLNCY) @GreenwaveGWAV @AngloAmerican @Glencore @LifezoneMetals @AlbemarleCorp

 

Why the Big Miners are Jumping in

 



June 20, 2024 –Investorideas.comgo-to platform for big investing ideas issues the second half of a two -part series looking at metals recycling.  The snapshot covers the growing demand and why big mining names are investing in the space, featuring Greenwave Technology Solutions, Inc. (Nasdaq:GWAV), an operator of metal recycling facilities in Virginia, North Carolina, and Ohio.

 

As demand for copper and other metals continues to rise, supply becomes a big issue. Just looking at copper alone, a recent forecast said, “Copper demand could double by 2035. The main drivers are the revival in demand from Chinese manufacturers, the rebound of the global economy and the boom in investments in green technologies (e.g. renewables and electrical vehicles) and in AI technologies.”

 

Continued: Supply is expected to grow but not as fast as demand. This is primarily due to two factors: the time required for new mine construction and the ageing of already existing mines.  Looking at the time lines, big names in mining are investing in the future of recycling in addition to the current players focusing strictly on recycling.

 

Greenwave Technology Solutions, Inc. (Nasdaq:GWAV), a leading operator of metal recycling facilities in Virginia, North Carolina and Ohio say on their website, ”SCRAP IS THE NEW PRECIOUS METAL.”

 

Earlier this week, Greenwave announced that it has completed its recapitalization and is on track to generate record revenues in excess of $40 million driven by volume of steel and copper processed in 2024

 

In May, Greenwave reported that it is expecting to generate revenues exceeding $40 million during the year ended December 31, 2024. Growth is being driven by its Cleveland, OH and Virginia Beach, VA locations. The Company expects its second American Pulverizer 60x85 shredder will result in the Company being EBITDA positive and generating positive cashflow from operating activities.

 

This article featuring Greenwave Technology Solutions, Inc. is paid for news dissemination.

 

Read this article, featuring GWAV in full at https://www.investorideas.com/news/2024/renewable-energy/06201Metals-Recycling.asp

 

"With a significantly strengthened balance sheet, I believe Greenwave is well positioned for the next phase of growth," stated Greenwave CEO, Danny Meeks. "The investments we've made in Greenwave's infrastructure will facilitate significant growth in our copper and steel processing capacity, which we anticipate will create significant shareholder value."

 

For its 2024 outlook, Greenwave says on its website, “The installation of Greenwave's second automotive shredder at its Carrollton facility to process cars, household appliances and industrial products in now complete. The shredder is expected to commence operation as soon as the electrical infrastructure is completed. Greenwave’s second automotive shredder is expected to come online this quarter and double the Company’s ferrous metal output. By selling its ferrous metal as shredded rather than unshredded, Greenwave generates approximately 25-30% more revenue with profit margins in excess of 60%.”

 

“The completion of Greenwave’s second automotive shredder concludes its multi-year capex cycle, under which the Company has invested more than $15 million in its infrastructure and equipment over the past 18 months. This capex cycle is expected to double its ferrous metal processing capacity from fiscal 2022 levels and result in the Company having the infrastructure to accretively scale its metal recycling.”

 

Big miners are also following the money trail and getting into the metals recycling game, including Anglo American (OTCQX:NGLOY) (LSE:AAL). Rio Tinto (NYSE: RIO) and Glencore plc. (OTC: GLNCY ) (LSE: GLEN).

 

As the Financial Post reported, “A US$700-million investment barely burns a hole in Rio Tinto Ltd.’s pocket. The sum is less than five per cent of its 2022 annual income of roughly US$16 billion and isn’t supposed to dominate headlines from a financial perspective.”

 

“But the mining giant’s Chief Executive, Jakob Stausholm will tell you that Rio’s recent purchase of a 50-per-cent stake in Brampton, Ont.-based Matalco Inc., a recycler of aluminum, is key to his company’s future and helped fill a gaping hole in its business.”

 

Getting the attention of some of the top mining investors, Lifezone Metals (NYSE: LZM), with a mission to provide cleaner and more responsible metals production and recycling, announced earlier this year, the signing of a binding subscription agreement for the issuance of US$50 million of convertible debentures with a consortium of marquee mining investors, led by Harry Lundin (Bromma Asset Management Inc.) and Rick Rule.

 

From the news: Proceeds will be used to continue activities at Lifezone’s flagship Kabanga Nickel Project, located in north-west Tanzania. Kabanga is believed to be one of the world’s largest and highest-grade undeveloped nickel sulfide deposits. The Kabanga Definitive Feasibility Study is on-track for completion in Q3 2024.

 

Last December, Lifezone announced the signing of a term sheet with a subsidiary of Glencore plc. (OTC: GLNCY) (LSE:GLEN) for a platinum, palladium and rhodium (collectively platinum group metals or “PGMs”) recycling project utilizing Lifezone Metals’ hydrometallurgical technology (“Hydromet”) to be based in the USA.

 

From the news: Phase 1 confirmatory piloting work has commenced in Perth, Australia using Hydromet to process and recover PGMs from responsibly sourced spent automotive catalytic converters.

 

From the news: Mr. Showalter stated, “By applying our Hydromet technology, we aim to responsibly recover platinum, palladium and rhodium from recycled sources in a cleaner and more efficient manner than otherwise possible through traditional smelting and refining. Following our acquisition of Simulus Labs in July, where we acquired the preeminent hydrometallurgical testing and engineering design group, we gained the capability to simultaneously advance our Kabanga Nickel Project through the continuing Definitive Feasibility Study while also investigating other important applications of our core Hydromet technology.”

 

Albemarle Corporation (NYSE:ALB), a leading provider of lithium, bromine and other essential elements. reports on its site, “As a market leader in battery grade lithium products, Albemarle and our R&D teams are committed to the development of an effective circular battery economy across the globe.”

 

Continued: The continued adoption of batteries for Mobility and Energy will require the deployment of technologies and infrastructure to incorporate spent batteries back into the supply chain. Recycled battery material drives more sustainable practices and improves resource security. The European Union has stipulated that by 2031 all batteries must contain 6% recycled lithium material and up to 12% by 2036. In the United States, batteries containing critical minerals recycled in North America are expected to support vehicle qualification for the Inflation Reduction Act consumer tax credit for EVs.

 

Continued: Recycling enables a closed-loop supply chain and comprises a series of steps that breaks down spent batteries into black mass, separates the different metal streams, and ultimately upgrades the waste streams into precursors for cathode manufacturing. We are using our expertise in refining lithium into high-purity products to get lithium sulfate from black mass back into the battery supply chain.

 

Grandview Research reports,”Growing environmental concerns about depletion of non-renewable resources, increasing harmful emissions from manufacturing plants, and improper waste disposal have led to the growth of the recycling industry, of which metal recycling constitutes a major part. Factors such as regulations about mining ores and increasing raw material prices are propelling the demand for recycled metal. The product reduces the manufacturing cost significantly, this benefit is further favoring its market growth.”

 

With big money at the table, and according to Researchandmarkets, the market projected to reach USD 767.9 billion by 2029, this sector is one to watch! 

 

Read part one of the series at Investorideas.com

https://www.investorideas.com/news/2024/renewable-energy/06181Recycling-Metal-Stocks.asp

 

Research more green stocks with Investorideas.com free stocks directory

https://www.investorideas.com/Companies/RenewableEnergy/Stock_List.asp

 

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Disclaimer/Disclosure: This article featuring Greenwave Technology Solutions, Inc. (Nasdaq: GWAV) s is a paid for content service on Investorideas. Our site does not make recommendations for purchases or sale of stocks, services or products. Nothing on our sites should be construed as an offer or solicitation to buy or sell products or securities. All investing involves risk and possible losses.  Contact management and IR of each company directly regarding specific questions. More disclaimer info: https://www.investorideas.com/About/Disclaimer.asp Learn more about publishing your news release and our other news services on the Investorideas.com newswire https://www.investorideas.com/News-Upload/ Global investors must adhere to regulations of each country. Please read Investorideas.com privacy policy: https://www.investorideas.com/About/Private_Policy.asp  

 

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The Uranium Story just got Bigger thanks to AI – (CSE: $PURR.CN) (OTC: $GLIOF) (NYSE: $URG) (NYSE: $NXE) (TSX: $NXE.TO) (TSXV: $SASK.V) (OTCQB: $SASKF) @PantherMinerals @Ur_Energy @NexGenEnergy_ @athaenergycorp

The Uranium Story just got Bigger thanks to AI – (CSE: $PURR.CN) (OTC: $GLIOF) (NYSE: $URG) (NYSE: $NXE) (TSX: $NXE.TO) (TSXV: $SASK.V) (OTCQB: $SASKF) @PantherMinerals @Ur_Energy @NexGenEnergy_ @athaenergycorp

 

Uranium Miners going Nuclear

 


June 20, 2024 -  Investorideas.com, a global investor news source covering mining and metals stocks releases a snapshot looking at uranium mining and exploration, featuring Panther Minerals Inc.(CSE: PURR) ) (OTC: GLIOF).

 

Panther Minerals Inc. is a mineral exploration company actively involved in the exploration of its North American project portfolio. The acquisition of the Boulder Creek Option reflects the Company's ongoing intention of pursuing advanced, highly quality prospective uranium projects that can be readily worked on and efficiently explored in a timely manner.

 

Uranium prices have had a big year, up over 52%  year to date, with some short term corrections. But the story for uranium miners just got bigger as AI (Artificial Intelligence) is changing the world as we know it and looks to nuclear energy to power its growth.

 

Nuclear energy already had significant tailwinds moving it forward as an energy of choice.  

In December at COP2), 22 countries agreed to triple global nuclear power capacity by 2050 to reach net zero ambitions.

 

Now, as top players like Microsoft fight for dominance in AI, they also are betting on nuclear power to reach their future goals. As AI grows faster than anyone anticipated, it is using up more electricity than our current systems had planned for.

 

Uranium miners and exploration companies see this growth boom as a new Bull Run opportunity.

 

Panther Minerals Inc.(CSE: PURR) (OTC: GLIOF) just issued a corporate update on its Boulder Creek Uranium property, located in the southeastern Seward Peninsula, 160 km east of Nome, Alaska (“Boulder Creek” or the “Property”).

 

This article featuring Panther Minerals Inc. (CSE: PURR) is a paid for service on Investorideas

 

Read this article, featuring PURR in full at https://www.investorideas.com/news/2024/mining/06201Uranium.asp

 

From the news: Panther Minerals has been completing ongoing compilation of all historical data available through previous work conducted by past operators of the Boulder Creek project, Houston Oil & Minerals and Triex Minerals (Full Metal Minerals). With significant historical data available, the Company is looking to continue a full review and analysis of drilling core located on the property and additional core located in Anchorage, Alaska. The data attained will give Panther Minerals a better understanding of the model and formation, as well as the opportunity to utilize its spectrometer to analyze and confirm radiometric readings.

 

From the news: Panther Minerals has submitted drill and work permits for its Boulder Creek property related to a proposal to conduct exploration activities, including diamond drilling, on active federal mining claims that comprise a portion of the Boulder Creek Uranium property, under option by the Company. The Company has engaged Jack DiMarchi, Core Geoscience LLC, to manage the Company’s permitting activities in Alaska. Additional permitting submittals will follow related to activities on the State claims and with regards to the proposed field camp. 

 

Ur-Energy Inc. (NYSE:URG), a uranium mining company operating the Lost Creek in-situ recovery uranium facility in south-central Wyoming is a miner well-known to investors in the sector. They have produced and packaged approximately 2.8 million pounds U3O8 from Lost Creek since the commencement of operations.

 

In May, when the Company announced its quarterly financials, Ur-Energy’s CEO, John Cash said in the news release, "Last week the US Senate, following the House of Representatives action on the same bill, announced the passage by unanimous consent of a Russian Uranium Ban that will commence 90 days after it is signed, subject to certain limited waivers available until January 1, 2028. We are encouraged to see unanimous bipartisan backing of a bill that is likely to result in strong support for western suppliers of nuclear fuel components, including Ur-Energy. We believe we are in the right place at the right time to help fill the uranium supply gap and we will continue to advance production at Lost Creek and Shirley Basin and look for other opportunities to expand our U.S. based production portfolio."

 

In their guidance for 2024 they said, “As uranium prices strengthened, we have received increasing requests for proposals ("RFPs") from utilities and other global fuel buyers. We have responded to the RFPs with prices commensurate with rising market conditions including increased demand for domestically produced uranium. We completed two additional uranium sales agreements during 2024 Q1 and a third agreement subsequent to quarter end. Including the three additional agreements, our contract book now stands at a total of 5.7 million pounds U3O8 with deliveries occurring in 2024 through 2030. Sales prices are anticipated to be profitable on an all-in production cost basis and escalate annually from initial pricing, including some market-based pricing features.”

 

NexGen Energy Ltd. (TSX: NXE) (NYSE: NXE) (ASX: NXG) announced on May 29th, drilling at Patterson Corridor East intersected mineralization in RK-24-193 over 67.5 metres (m) (383.5 to 451 m) across various intervals including up to 7,500 cps over 1.5 m (Figures 1 to 4, Table 1). RK-24-193 is located 275 m southwest along strike of RK-24-183 (discovery hole) and at approximately the same depth below surface.

 

In addition, assays from RK-24-183 confirm high grade uranium veins across a 20 m interval with several intersections totalling 13.5 m at 0.78% U3O8 including 0.5 m (348.0 to 348.5 m) at 10% U3O8 and another 0.5 m (356.5 to 357 m) at 6.23% U3O8 (Table 2). For reference, the Arrow discovery hole RK-14-21 assayed 5.75 m at 0.37% U3O8, including 0.25 m at 5.77% U3O8.

 

Leigh Curyer, Chief Executive Officer commented: "Our team has assessed the geological similarities between RK-24-183 and RK-24-193 and the upper areas of Arrow, which indicates the high prospectivity of an additional mineralized system 3.5 km east of Arrow. Consequently, the growing potential of this latest discovery will drive the focus of the summer exploration program to determine the potential size and extent of mineralization. Efficient and bold testing of the overall system is the first priority.

 

It is an exciting time at NexGen with the Company recently advancing the Federal Environmental Assessment process for the Rook I Project through the submission of responses to the remaining Information Requests, as well as advancing detailed engineering and exploring a new discovery in parallel."

 

ATHA Energy Corp. (TSX.V:SASK) (OTCQB:SASKF) holder of the largest uranium exploration portfolio in two of the highest-grade uranium districts in the world, announced earlier this month that the Company has commenced Phase I (diamond drilling) of its 2024 Angilak Exploration Program at its 100%-owned Angilak Project in Nunavut. Phase I is comprised of ~10,000 m of diamond drilling targeting the expansion of high-grade uranium mineralization at the Lac 50 Deposit and adjacent mineralized zones.

 

From the news: HIGHLIGHTS:

Angilak Project: The Angilak Project is host to the Lac 50 Uranium Deposit, which is one of the largest high-grade deposits outside of the Athabasca Basin, with a historical mineral resource estimate of 43.3M lbs. at an average grade of 0.69% U3O8.1 Drilling in 2023 by Latitude Uranium (acquired by ATHA) intersected grades of up to 7.54 % U3O8 over 1.6 m.

 

2024 Angilak Exploration Program is part of the Company’s overall 2024 Exploration Program and consists of Phase I (diamond drilling) and Phase II (geophysics & ground geochemistry).

 

As far as what uranium stocks will winners and losers, maybe investors can ask the giant fuelling this boom, ChatGPT, and see what it says.

 

For additional insight into Panther Minerals Inc. (CSE: PURR) listen to the recent Exploring Mining Podcast Interview

 

Listen to the podcast:

https://www.spreaker.com/episode/panther-minerals-inc-the-hunt-for-uranium-in-alaska--60389196

 

Watch on YouTube:

https://youtu.be/XMqJX1aCwu8

 

Research mining stocks at Investorideas.com with our mining stocks directory at Investorideas.com https://www.investorideas.com/Gold_Stocks/Stocks_List.asp 

 

About Investorideas.com - Big Investing Ideas

Investorideas.com is the go-to platform for big investing ideas. From breaking stock news to top-rated investing podcasts, we cover it all. Our original branded content includes podcasts such as Exploring Mining, Cleantech, Crypto Corner, Cannabis News, and the AI Eye. We also create free investor stock directories for sectors including mining, crypto, renewable energy, gaming, biotech, tech, sports and more. Public companies within the sectors we cover can use our news publishing and content creation services to help tell their story to interested investors. Paid content is always disclosed.

 

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Cancer Treatment stocks to watch (NASDAQ: $AEMD) (NYSE: $MRK) (NYSE: $BMY) (NYSE: $ABBV) @Merck @bmsnews @abbvie

 

Cancer Treatment stocks to watch (NASDAQ: $AEMD) (NYSE: $MRK) (NYSE: $BMY) (NYSE: $ABBV) @Merck @bmsnews @abbvie

 

What’s next in Treatments for Cancer Patients with Solid Tumors?



June 20, 2024 - Investorideas.com, a go-to investing platform, releases an industry snapshot  looking at the future treatment of solid cancer tumors, featuring Aethlon Medical, Inc. (Nasdaq:AEMD), a medical therapeutic company focused on developing products to treat cancer and life-threatening infectious diseases.

 

Research released this year predicts, “The solid tumor therapeutics market size will grow from USD 222.71 Billion in 2023 to USD 885.44 Billion in 10 years. Increasing investments of pharmaceutical companies in Research & Development will drive the solid tumor therapeutics market's growth. North America emerged as the largest market for the global Solid Tumor Therapeutics market, accounting for 44% of the total market share globally.”

 

Current drugs available including Merck & Co., Inc.’s (NYSE:MRKKeytruda® (pembrolizumab) and Bristol Myers Squibb’s (NYSE: BMY) Opdivo® (nivolumab), solve part of the problem but the success rates call for additional solutions.   

 

Aethlon Medical, Inc. (Nasdaq: AEMD) announced this week that, on June, 13, 2024, the Human Research Ethics Committee (HREC) of the Central Adelaide Local Health Network (CALHN) granted full ethics approval for Aethlon’s safety, feasibility and dose-finding clinical trial of the Hemopurifier® in cancer patients with solid tumors who have stable or progressive disease during anti-PD-1 monotherapy treatment, such as Keytruda® (pembrolizumab) or Opdivo® (nivolumab) (AEMD-2022-06 Hemopurifier® Study). The approval is valid for three years, until June 13, 2027. The trial will be conducted by Prof. Michael Brown and his staff at the Cancer Clinical Trials Unit, CALHN, Royal Adelaide Hospital, located in Adelaide, Australia.

 

Currently, only approximately 30% of patients who receive pembrolizumab or nivolumab will have lasting clinical responses to these agents. Extracellular vesicles (EVs) produced by tumors have been implicated in the spread of cancers as well as the resistance to anti-PD-1 therapies. The Aethlon Hemopurifier® has been designed to bind and remove these EVs from the bloodstream, which may improve therapeutic response rates to anti-PD-1 antibodies. In preclinical studies, the Hemopurifier® has been shown to reduce the number of exosomes from the plasma of cancer patient samples.

 

This article featuring Aethlon Medical, Inc. is paid for news dissemination

 

Read this article featuring AEMD in full at https://www.investorideas.com/news/2024/biotech/06201Cancer-Treatment-Stocks.asp

 

"The approval from the Human Research Ethics Committee at Central Adelaide Local Health Network marks a significant milestone for Aethlon, as they deemed that our clinical study meets the requirements of the Australia’s National Statement on Ethical Conduct in Human Research,” stated Steven LaRosa, MD, Chief Medical Officer of Aethlon Medical. “We look forward to working closely with Prof. Brown and his staff, and with our Contract Research Organizations, NAMSA and ReSQClinical Research. The next steps include submission to the Therapeutic Goods Administration, the national health regulatory agency of Australia, obtaining approval from the CALHN Research Governance Committee, and conducting a site initiation visit to facilitate patient enrollment. Following this Ethics Board approval, we plan to submit to the Ethics Committees at two additional sites in Australia and one in India.” 

 

The primary endpoint of the approximate 18-patient, safety, feasibility and dose-finding trial is safety. The trial will monitorany adverse events and clinically significant changes in lab tests of Hemopurifier® treated patients with solid tumors with stable or progressive disease at different treatment intervals, after a two-month run in period of PD-1 antibody, Keytruda® or Opdivo® monotherapy. Patients who do not respond to the therapy will be eligible to enter the Hemopurifier® period of the study where sequential cohorts will receive 1, 2 or 3 Hemopurifier® treatments during a one-week period. In addition to monitoring safety, the study is designed to examine the number of Hemopurifier® treatments needed to decrease the concentration of EVs and if these changes in EV concentrations improve the body’s own natural ability to attack tumor cells. These exploratory central laboratory analyses are expected to inform the design of a subsequent efficacy and safety, Premarket Approval (PMA), study required by regulatory agencies.

 

In May, Bristol Myers Squibb (NYSE:BMYannounced that the US Food and Drug Administration (USFDA) has reassigned the previously announced Prescription Drug User Fee Act (PDUFA) goal date of the Biologics License Application (BLA) for the subcutaneous formulation of Opdivo® (nivolumab) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20) (herein referred to as “subcutaneous nivolumab”) across all previously approved adult, solid tumor Opdivo indications as monotherapy, monotherapy maintenance following completion of Opdivo® plus Yervoy (ipilimumab) combination therapy, or in combination with chemotherapy or cabozantinib. The updated goal date is December 29, 2024.

 

From news: The application is based on results from CheckMate-67T, the first Phase 3 trial of the subcutaneous formulation of nivolumab to evaluate and demonstrate non-inferior pharmacokinetics, efficacy and consistent safety vs. its intravenous formulation. If approved, subcutaneous nivolumab has the potential to be the first and only subcutaneously administered PD-1 inhibitor.

 

From news: CheckMate-67T is a Phase 3 randomized, open-label trial evaluating subcutaneous administration of Opdivo® co-formulated with Halozyme’s proprietary recombinant human hyaluronidase, rHuPH20, or subcutaneous nivolumab (nivolumab and hyaluronidase) compared to intravenous Opdivo, in patients with advanced or metastatic clear cell renal cell carcinoma (ccRCC) who have received prior systemic therapy. This trial presents an opportunity to potentially bring a subcutaneous formulation of Opdivo® to patients. A total of 495 patients were randomized to either subcutaneous nivolumab or intravenous Opdivo®. The co-primary endpoints of the trial are time-averaged serum concentration over 28 days (Cavgd28) and trough serum concentration at steady-state (Cminss) of subcutaneous nivolumab vs. intravenous Opdivo®. Objective response rate (ORR) is a key secondary endpoint.

 

According to Merck & Co., Inc. (NYSE:MRK), “KEYTRUDA is not chemotherapy or radiation therapy-it is an immunotherapy and it works with your immune system to help fight cancer. KEYTRUDA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become serious or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended.”

 

Looking at key developments in the solid tumor market, BrainyInsights reported that In November 2023, AbbVie (NYSE:ABBV) acquired ImmunoGen. The main objective behind this acquisition was to build and expand a strong portfolio base for the Solid Tumor Therapeutics Market. This acquisition will further boost AbbVie’s entry into the commercial market for ovarian cancer.

 

In May, AbbVie showcased its “Robust Solid Tumor Pipeline at ASCO 2024 with New Data from Its Innovative Antibody-Drug Conjugate (ADC) Platform.”

 

From the news: "Building upon our strong commitment to patients and existing leadership in hematological malignancies, we are rapidly advancing a differentiated pipeline in solid tumors," said Daejin Abidoye, M.D., Vice President, Head of Solid Tumors, Oncology Development, AbbVie. "Our ADC platform allows us to utilize selected biomarkers such as c-Met and SEZ6 to induce targeted cancer cell death by delivering potent anti-cancer agents. The data we are presenting at ASCO demonstrate the clinical potential of this approach across a wide range of difficult-to-treat tumors."

 

From the news: Data from the dose-escalation and colorectal cancer (CRC) dose-expansion cohort of an ongoing first-in-human Phase 1 study (NCT05029882) of ABBV-400, a potential best-in-class c-Met directed ADC, will be presented in an oral presentation. The preliminary data show that among 122 heavily pre-treated advanced CRC patients, promising antitumor activity was observed at 2.4 and 3.0 mg/kg doses administered once every 3 weeks, with confirmed objective response rate (ORR) of 18% (n=40) and 24% (n=41) respectively in those groups. In patients with higher c-Met expression, ORR was enriched to >35% at doses ≥2.4 mg/kg. The most common Gr≥3 treatment-emergent adverse events (TEAEs) were anemia (35%), neutropenia (7%) and febrile neutropenia (6%). TEAEs leading to discontinuation occurred in 25 (20.5%) patients. Additional data will be presented at the meeting.

 

From the news: ABBV-400 is also being evaluated in a Phase 1b basket study (NCT06084481) in advanced solid tumors as a monotherapy and a Phase 2 study (NCT06107413) in second line metastatic CRC in combination with fluorouracil, folinic acid, and bevacizumab.

 

From their Solid Tumor market report, BrainyInsights also says, A huge chunk of pharmaceutical companies continue to make significant contributions to the development of experimental drugs and technologies. The pharmaceutical sector, for instance, is significantly invested in research and development. Pharmaceutical firms invest in future research to bring high-quality, pharmaceuticals to the marketplace. Major pharma firms are boosting their R&D efficiency by investing heavily in R&D, to ensure long returns on investments, as well as by collaborating with R&D centres worldwide. for instance: According to Statista, Roche is expected to be the world’s largest company which is investing heavily in R&D, that is, USD 14 Billion followed by Johnson & Johnson (USD 12.2 Billion), Merck & Co (USD 11.4 Billion), Pfizer (USD 10.5 Billion) and Novartis (USD 10 Billion), by the year 2026.

 

Aethlon Medical, Inc. (Nasdaq: AEMDsays it initiated its tumor-derived exosome research at a time when the medical community believed exosomes were merely cellular debris with no biological function. Today, a therapeutic to address tumor-derived exosomes represents a significant unmet need in cancer care. Aethlon has demonstrated that the affinity mechanism of the Hemopurifier® can capture tumor-derived exosomes and exosomal particles underlying several forms of cancer, including breast, ovarian and metastatic melanoma.

 

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Biotech Industry Stocks- investing ideas in biotechnology stocks, medical technology and life sciences

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